BDBM323718 US10188756, Compound CN149::US11207431, Example B

SMILES CN(Cc1ccc(\C=C\C(=O)NO)cc1F)CC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=JJVJGQDLQUPOQJ-HWKANZROSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323718   

TargetHistone deacetylase 3(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM323718(US10188756, Compound CN149 | US11207431, Example B)
Affinity DataIC50:  0.760nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM323718(US10188756, Compound CN149 | US11207431, Example B)
Affinity DataIC50:  23nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent